At evening, Officer Kevin Ryman and the other refugees collected special gems which opened a statue, providing a small ventilation shaft to the outside. One of the police officers; Rita, left through the tunnels under the statue to escape and get help. However, by the time she returned with a van driven by fellow police officer Harry, three of the officers were already dead. The only people to get on the van were the refugees and Kevin, while Marvin Branagh stayed behind after getting bitten and infected by a zombie.
In the early hours of Sept. 28th, Officer Ford finally succumbed and committed suicide. Three more officers were killed by a zombie attack. Elliot Edward took over and attempted to lead the remaining three officers Elliot; Eric and Harry escape into the sewers, They later attempt to wire a bomb to eliminate the zombie horde on Main Street but are overrun before finishing it, leaving only Harry alive. Survivors happen upon the scene moments after and finish wiring the bomb detonating it killing all the zombies on Main Street. Later on the same day, former S.T.A.R.S. officer Jill Valentine explored parts of the department whilst on the run from the Nemesis. There she saw Marvin, who at the time was still alive, but unconscious.
On September 29, more survivors found their way into the precinct for differing reasons. Claire Redfield, sister of S.T.A.R.S. member Chris Redfield. Leon S. Kennedy, a new rookie officer late for his first day. Sherry Birkin, daughter of Umbrella virologist William Birkin, who was sent to the station for her safety by her mother, Annette Birkin. Ada Wong, a spy secretly working for Albert Wesker, and lastly, HUNK, a commando from the U.S.S. sent to retrieve a sample of the G-Virus created by William Birkin.
An unknown, surviving officer fled to the precinct rooftop where he attempted to board a police helicopter out of the city. The rescue attempt went wrong however when the officer was ambushed by zombies and accidentally hit the pilot with stray machine gun fire, sending the helicopter crashing into the building. Later, an Umbrella helicopter dropped a capsule containing the Tyrant (T-103 Model), known as T-00 to stalk the survivors in the R.P.D. for the G-virus.
Claire found a dying Marvin, who gave Leon a keycard to unlock the rest of the station's doors. Marvin later succumbed to the t-Virus and became a zombie. Claire was forced to kill him.
Claire found her way into the Chief's office where she saw Irons with the freshly-killed corpse of the Mayor's daughter, up until this point a survivor. Claire found Sherry in the building and they attempted to leave the precinct via a secret passage behind Irons' bookshelf. The infected, mutated William Birkin later found his way into the passage via the sewers and impregnated Irons with a G-embryo. He then died in agonizing pain from the parasite in his body.
Meanwhile, Leon met Ada for the first time in the car park, where they moved the Police van out of the way (it was previously in the ramp) and discovered the only surviving prisoner, Ben Bertolucci. Ben divulged information about a passage into the sewers inside the kennels, but was later attacked by the mutated Birkin. Leon and Ada rushed to his aid and Ben handed over damning evidence of Chief Irons' corruption before dying.