主题：端粒结构生物学研究进展

学习工作经历：
1995-1999 武汉大学 生命科学学院，生物化学 本科
1999-2004 武汉大学 生物物理与生物化学 博士
2004.12-2007.06 博士后，中科院水生生物研究所
2007.06-2010.12 博士后，美国密歇根大学医学院
2010.12-2012.06　 副教授，南开大学生命科学学院
2012.07-至今 教授，华中农业大学生命科学技术学院
研究方向：结构生物学
最近研究成果：
1.Feng Wang, Mingliang Tang, Zhixiong Zeng, Renyi Wu, Yong Xue, Yuhua Hao, Daiwen Pang, Yong Zhao, Zheng Tan. (2012) A telomere and telomerase interacting protein that unfolds telomere G-quadruplex and promotes telomere extension in mammalian cells. Proc.Natl. Acad. Sci. USA. 2012, Nov 26. （IF=10.231）
2.Zhixiong Zeng, Bosun Ming, Jing huang, Kyungah Hong, Yuting Yang, Kathleen Collins, Ming Lei. Structural basis for Tetrahymena telomerase processivity factor Teb1 binding to single-stranded telomeric-repeat DNA. Proc Natl Acad Sci U S A. 2011, 108(51): 20357-61. （IF=10.231）
3.Zhixiong Zeng, Wei Wang, Yuting Yang, Yong Chen, Xiaomei Yang, J. Alan Diehl, Xuedong Liu, Ming Lei. Structural basis of selective ubiquitination of TRF1 by SCFFBX4. Dev. Cell. 2010, 18 (2): 214-225. （IF=14.058）
4.Yong Zhao, Zhi-xiong Zeng, Zhong-yuan Kan, Yu-hua Hao, and Zheng Tan. The Folding and Unfolding Kinetics of the I-Motif Structure Formed by the C-Rich Strand of Human Telomere DNA.ChemBioChem. 2005, 6(11): 1957-60. (IF=3.824)
5.Zhi-xiong Zeng, Yong Zhao, Yu-hua Hao, Zheng Tan. Tetraplex Formation of Surface-immobilized Human Telomere Sequence Probed by Surface Plasmon Resonance Using Single-stranded DNA Binding Protein. J. Mol. Recognit. 2004, 18(3): 267-71. (IF=2.776)
6.Yong Zhao, Zhong-yuan Kan, Zhi-xiong Zeng, Yu-hua Hao, Hua Chen, Zheng Tan. Determining the Folding and Unfolding Rate Constants of Nucleic Acids by Biosensor. Application to Telomere G-Quadruplex. J Am Chem Soc. 2004, 126(41): 13255-64. (IF=9.019)

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